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Thyroglobulin

Pathology

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Thyroglobulin test is to monitor treatment of thyroid cancer and to detect recurrence; less commonly, to help determine the cause of hyperthyroidism and hypothyroidism

Prior to and after the completion of treatment for thyroid cancer, before and after radioactive iodine therapy, and at regular intervals to monitor for recurrence; this test may be ordered in conjunction with other thyroid tests for certain thyroid disorders.

The reference range of thyroglobulin in euthyroid persons without thyroglobulin antibody (TgAb) using CRM-457 standards is 3-40 ng/mL in countries with adequate iodide intake. In about 8% of the general population, thyroglobulin values are less than 10 ng/mL.

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