Antiphospholipid antibodies (APA) are a group of autoantibodies that bind to negatively charged phospholipids. These antibodies have been associated with thrombotic events which could lead to pregnancy loss, venous and arterial thrombosis and thrombocytopenia. They prevent the blood to flow properly resulting in blood clots causing a health risk to both the mother and the baby. Some important types of phospholipid antibodies are: anticardiolipin; antinuclear and lupus antibodies.
The antiphosolipid antibody test detects increased levels of various antibodies. The process helps detect any particular set of specimens. It is an essential process in the body’s ability to regulate the clotting of blood. It helps diagnose the reasons for recurrent miscarriage; asses or monitor a prolonged PTT (partial thromboplastin time) or assess the antiphospholipid antibody syndrome.
The reference range findings are as follows: Less than 15 immunoglobulin G (IgG) phospholipids units (GPL): Absent or none detected. Less than 12 immunoglobulin M (IgM) phospholipids units (MPL): Absent or none detected.
