Scl 70 antibodies are considered to be specific for scleroderma (systemic sclerosis) and are found in up to 60% of patients with this connective tissue disease.
Anti Scl – 70 test is to evaluate patients with signs and symptoms of scleroderma and other connective tissue diseases in whom the test for antinuclear antibodies is positive.
A positive test result for Scl 70 antibodies is consistent with a diagnosis of scleroderma.