Anti-double-stranded DNA or Anti-dsDNA is to diagnose and monitor lupus (systemic lupus erythematosus, SLE). This test is to be done when you have a positive ANA test and signs and symptoms associated with lupus, such as persistent fatigue and weakness, arthritis-like pain in one or more joints, a red rash resembling a butterfly across the nose and cheeks, and/or skin sensitivity to light; periodically when you have been diagnosed with lupus.
Evaluating patients with signs and symptoms consistent with systemic lupus erythematosus (SLE). Monitoring patients with documented SLE for flares in disease activity
<30.0 IU/mL (negative) 30.0-75.0 IU/mL (borderline) >75.0 IU/mL (positive)
Negative is considered normal.
Reference values apply to all ages.